PULMONARY EMPHYSEMA AND FIBROSIS

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Combined pulmonary fibrosis and emphysema.

Combined pulmonary fibrosis and emphysema (CPFE) is a distinct clinical entity characterized by the simultaneous coexistence of both upper lobe emphysema and lower lobe pulmonary fibrosis. Although it was first described in 1990, it has not received enough recognition. Due to its unique lung function and clinical profile, pulmonologists should be aware of its existence while evaluating patients...

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Idiopathic pulmonary fibrosis with emphysema: evidence of synergy among emphysema and idiopathic pulmonary fibrosis in smokers.

BACKGROUND Emphysema and fibrosis, typically the idiopathic pulmonary fibrosis (IPF) form of usual interstitial pneumonia (UIP), can co-exist as combined pulmonary fibrosis emphysema (CPFE). It is unknown whether there is a pathobiologic basis for CPFE beyond the coexistence of fibrosis and emphysema. The aim of this study was to ascertain radiologic differences in severity of fibrosis and emph...

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Combined Pulmonary Fibrosis and Emphysema (CPFE)

Emphysema is characterized by the permanent abnormal enlargement of airspaces distal to the terminal bronchioles, accompanied by destruction of their walls. The characteristics of emphysema do not, by definition, include thickening of the alveolar septa and fibrosis. However, coincidental idiopathic pulmonary fibrosis (IPF) and emphysema was firstly reported in 1990 by Wiggins et al (Wiggins J,...

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The impact of emphysema in pulmonary fibrosis.

Several groups have described a syndrome in which idiopathic pulmonary fibrosis (IPF) coexists with pulmonary emphysema. This comes as no surprise since both diseases are associated with a history of exposure to cigarette smoke. The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is characterised by upper lobe emphysema and lower lobe fibrosis. Physiological testing of these patien...

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Clinical characteristics in Combined Pulmonary Fibrosis and Emphysema Syndrome vs Idiopathic Pulmonary Fibrosis patients

Abstract: Aim: To identify differences between combined pulmonary fibrosis and emphysema syndrome (CPFE) and idiopathic pulmonary fibrosis (IPF) by a retrospective comparison of clinical data including clinical characteristics and baseline changes in pulmonary function. Methods: We studied demographic, clinical and physiologic features for two groups of patients, (total N=26) those with CPFE (7...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 1977

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.66.1688